MyBioSource.com's Mouse monoclonal IMP3 antibody is a Human, and Mouse monoclonal antibody. The Mouse monoclonal IMP3 antibody was generated using IGF2BP3, and mimp3 as the antigen. It reacts with Human. This antibody has been shown to work in applications such as: Western Blot.
Description
RNA-binding protein that act as a regulator of mRNA translation and stability.Binds to the 5´-UTR of the insulin-like growth factor 2 (IGF2) mRNAs.Binds to sequences in the 3´-UTR of CD44 mRNA.
The protein encoded by this gene is primarily found in the nucleolus,where it can bind to the 5´ UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development.The encoded protein contains several KH domains,which are important in RNA binding and are known to be involved in RNA synthesis and metabolism.A pseudogene exists on chromosome 7,and there are putative pseudogenes on other chromosomes.[provided by RefSeq,Jul 2008]